According to CoinMeta, Anthropic has adjusted the biosafety restrictions of Claude Fable 5. Previously, once a biological issue triggered the security classifier, it would automatically switch to the less capable Opus 5. After the new version of the classifier was launched, there was a reduction of about 85% in bioscience-related regressions during testing. For common issues such as interpreting test results, understanding symptoms, and learning biology, it is now easier to directly use Fable 5.